Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268586 | 0.84 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL7041079 | 0.83 | ATM (0.54) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL10709493 | 0.83 | CES2 (0.52) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL1104605 | 0.81 | KMT2A (0.61) | RAB9ASMN1; SMN2KMT2AMAOAMAOB | |
| SCHEMBL10036561 | 0.81 | PARP10 (0.46) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL566413 | 0.81 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2POLBRXRA | |
| SCHEMBL7201649 | 0.80 | ALDH1A1 (0.60) | NPC1SMN1; SMN2MEN1KMT2AMAOA | |
| SCHEMBL2607023 | 0.79 | LOXL2 (0.66) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL25804197 | 0.79 | PARP10 (0.44) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL8280582 | 0.79 | PARP10 (0.63) | NPC1RAB9AKMT2AMAOBLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025073682-A1 | METHOD FOR THE KETONE FUNCTIONALISATION OF POLYETHYLENES AND COPOLYMERS CONTAINING ETHYLENE UNITS AND 1,3-DIENE UNITS | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2025-04-10 | — | — | WO | disclosed |
| EP-0174088-B1 | BIOLOGICALLY ACTIVE AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | disclosed |
| CN-1013112-B | Method for producing biologically active amide derivatives and their use for controlling plants | IMP CHEMCIAL IND PLC (GB) | 1991-07-10 | — | — | CN | disclosed |
| US-4808628-A | NONPHYTOTOXIC | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-28 | — | — | US | disclosed |
| US-4728665-A | SYSTEMIC | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-01 | — | — | US | disclosed |
| CN-85106796-A | The preparation method of bioactive amide derivatives and the purposes of controlling plant thereof | — | 1987-04-22 | — | — | CN | disclosed |
| EP-0174088-A2 | Biologically active amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-03-12 | — | — | EP | disclosed |