Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 8/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.46 |
| ▸ | NLN | Q9BYT8 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877578 | 0.83 | CPA1 (0.38) | ADRA2AADRA2BADRA2CNLN | |
| SCHEMBL28027221 | 0.73 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL27561367 | 0.71 | CYP19A1 (0.46) | — | |
| SCHEMBL29176090 | 0.68 | HRH4 (0.43) | — | |
| SCHEMBL29853 | 0.66 | NPC1 (0.54) | — | |
| SCHEMBL29176086 | 0.65 | HRH4 (0.35) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL21401254 | 0.64 | ADRA1D (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL9572843 | 0.64 | CYP2C9 (0.40) | — | |
| SCHEMBL25888 | 0.63 | MTNR1A (0.45) | — | |
| SCHEMBL21401251 | 0.63 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104797570-A | Pyridine derivatives | TEIJIN PHARMA LTD | 2015-07-22 | — | — | CN | disclosed |