Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027249 | 0.89 | NOS3 (0.45) | DHODHPDE10ATSHRSMN1; SMN2TLR8 | |
| SCHEMBL13758058 | 0.86 | PDE10A (0.60) | DHODHPDE10ATSHRTDP1TOP1 | |
| SCHEMBL28027246 | 0.84 | DHODH (0.55) | DHODHTAAR1 | |
| SCHEMBL28159695 | 0.83 | TDP1 (0.66) | DHODHPDE10ATSHRTDP1TOP1 | |
| SCHEMBL27651467 | 0.81 | TAAR1 (0.55) | TSHRTAAR1TDP1LMNASMN1; SMN2 | |
| SCHEMBL28027827 | 0.81 | ADORA2A (0.53) | DHODHPDE10ATSHRTDP1TOP1 | |
| SCHEMBL28027826 | 0.81 | KDM4E (0.62) | DHODHPDE10ATSHRTDP1TOP1 | |
| SCHEMBL28027828 | 0.81 | KDM4E (0.62) | DHODHPDE10ATSHRTDP1TOP1 | |
| SCHEMBL28159698 | 0.81 | DHODH (0.52) | DHODHPDE10ATSHRTDP1TOP1 | |
| SCHEMBL14119243 | 0.80 | TAAR1 (0.63) | TAAR1TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817496-B | A kind of 1,2,3,4 tetrahydroquinoline derivatives and preparation method thereof | 中国科学院化学研究所 | 2017-06-16 | — | — | CN | disclosed |
| CN-104817496-A | 1, 2, 3, 4-tetrahydroquinoline derivative and method for preparing same | CHINESE ACAD INST CHEMISTRY | 2015-08-05 | — | — | CN | disclosed |