Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 12/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605365 | 0.83 | MAOA (0.41) | ALDH1A1HPGDMAPTMAOAKDM4E | |
| SCHEMBL3605401 | 0.83 | MAOA (0.41) | ALDH1A1HPGDMAPTMAOAKDM4E | |
| SCHEMBL3601616 | 0.76 | MAOA (0.44) | ALDH1A1HPGDMAPTMAOAMAOB | |
| SCHEMBL4087620 | 0.76 | TDP1 (0.42) | ALDH1A1HPGDMAPTMAOAKDM4E | |
| SCHEMBL3607469 | 0.72 | TDP1 (0.37) | ALDH1A1HPGDMAPTMAOAKDM4E | |
| SCHEMBL657796 | 0.72 | MAOA (0.47) | ALDH1A1MAOAKDM4ETSHRMAOB | |
| SCHEMBL3594388 | 0.70 | ACHE (0.38) | ALDH1A1HPGDMAPTMAOAKDM4E | |
| SCHEMBL7947753 | 0.68 | KDM4E (0.47) | ALDH1A1HPGDMAPTMAOAKDM4E | |
| SCHEMBL22791651 | 0.65 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTMAOAKDM4E | |
| SCHEMBL11377137 | 0.65 | PBRM1 (0.58) | ALDH1A1MAPTMAOAKDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |