Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027386 | 0.76 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL1974835 | 0.73 | BRD4 (0.55) | BRD4CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL1745297 | 0.72 | BRD4 (0.58) | BRD4CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL205804 | 0.70 | BRD4 (0.53) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL3936527 | 0.70 | BRD4 (0.49) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL204537 | 0.69 | BRD4 (0.46) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL204011 | 0.69 | BRD4 (0.46) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL205798 | 0.67 | BRD4 (0.53) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL9914787 | 0.67 | BRD4 (0.51) | BRD4CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL2022257 | 0.67 | BRD4 (0.49) | BRD4TRIM24TRIM33CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |