SCHEMBL28027936

SCHEMBL28027936

O=CC(=O)c1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16922260 0.85
SCHEMBL28027939 0.77 ALDH1A1 (0.67)
SCHEMBL175249 0.77 ALDH1A1 (0.67)
Formic Acid SCHEMBL31678789 0.75 ALDH1A1 (0.53)
SCHEMBL18153600 0.75 JAK2 (0.51)
SCHEMBL18153601 0.75 JAK2 (0.51)
SCHEMBL2170448 0.75
SCHEMBL121301 0.75
Hydrochloric Acid SCHEMBL27980177 0.75 ALDH1A1 (0.64)
SCHEMBL10285238 0.74 ALDH1A1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870429-A Benzofuran derivative, preparation method therefor, and medical application thereof SICHUAN HAISCO PHARMACEUTICAL CO LTD 2015-08-26 CN claimed
CN-104870429-A Benzofuran derivative, preparation method therefor, and medical application thereof SICHUAN HAISCO PHARMACEUTICAL CO LTD 2015-08-26 CN disclosed