Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027971 | 0.80 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL28027434 | 0.80 | FFAR1 (0.33) | FFAR1 | |
| SCHEMBL28027429 | 0.80 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL5102053 | 0.79 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL5115209 | 0.75 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL92954 | 0.73 | NAAA (0.47) | — | |
| SCHEMBL5102120 | 0.72 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL92943 | 0.69 | KDM4C (0.41) | — | |
| SCHEMBL23662562 | 0.69 | DHFR (0.43) | — | |
| SCHEMBL8632096 | 0.67 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |