SCHEMBL28028096

SCHEMBL28028096

CS(=O)(=O)Oc1ccc(S(=O)(=O)c2ccc(OS(=O)(=O)C(F)(F)F)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.47
CXCR2 P25025 2/20 0.46
CXCR1 P25024 1/20 0.44
MMP2 P08253 2/20 0.43
MMP7 P09237 2/20 0.43
MMP9 P14780 2/20 0.43
MMP14 P50281 2/20 0.43
HSD11B1 P28845 2/20 0.43
MMP1 P03956 1/20 0.43
ELANE P08246 2/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
GAA P10253 2/20 0.41
MMP3 P08254 1/20 0.40
MMP8 P22894 1/20 0.40
ALDH1A1 P00352 2/20 0.40
PTPN1 P18031 1/20 0.38
DRD2 P14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822779 0.91 PKM (0.50) PKMCXCR2CXCR1HSD11B1ELANE
SCHEMBL19564840 0.86 HTT (0.59) PKMCXCR2CXCR1HSD11B1ELANE
SCHEMBL20924560 0.86 PKM (0.68) PKMCXCR2MMP2MMP9MMP14
SCHEMBL3671604 0.85 HTT (0.53) PKMCXCR2HSD11B1ELANEHTT
SCHEMBL4150360 0.85 HTR6 (0.54) PKMCXCR2HSD11B1ELANEHTT
SCHEMBL28028097 0.83 PKM (0.56) PKMCXCR2CXCR1HSD11B1ELANE
SCHEMBL11700896 0.83 CXCR2 (0.49) CXCR2CXCR1CA1CA2CA9
SCHEMBL811054 0.82 PKM (0.58) PKMCXCR2CXCR1HSD11B1ELANE
SCHEMBL3675391 0.81 HTT (0.56) PKMMMP2MMP7MMP9MMP14
SCHEMBL576035 0.80 CA2 (0.50) CXCR2CXCR1HSD11B1PTPN1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105137508-B Compound, optical material and optical element used for optical elements 佳能株式会社 2019-11-08 CN disclosed
CN-105137508-A ACRYLATE COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KK 2015-12-09 CN disclosed
CN-102260201-B Compound for optical element, optical material, and optical element CANON KABUSHIKI KAISHA (JP) 2015-10-14 CN disclosed