Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 5/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028172 | 0.76 | MEN1 (0.41) | CAPN1MEN1TSHRKMT2AREN | |
| SCHEMBL28028159 | 0.75 | CAPN1 (0.46) | CAPN1RENCTSKCTSSCTSL | |
| SCHEMBL28821803 | 0.73 | MEN1 (0.44) | CAPN1MEN1TSHRKMT2ACTSD | |
| SCHEMBL15299885 | 0.69 | MEN1 (0.47) | CAPN1MEN1TSHRKMT2AREN | |
| SCHEMBL21457955 | 0.68 | CAPN1 (0.61) | CAPN1RENCTSKCTSL | |
| SCHEMBL4391534 | 0.68 | CAPN1 (0.61) | CAPN1RENCTSKCTSL | |
| SCHEMBL28028183 | 0.68 | PSMB5 (0.37) | RENCTSDCTSKPSMB5 | |
| SCHEMBL28027550 | 0.65 | REN (0.40) | RENCTSDPSMB5 | |
| SCHEMBL21458026 | 0.65 | MEN1 (0.46) | CAPN1MEN1TSHRKMT2AREN | |
| SCHEMBL21555137 | 0.63 | SMN1; SMN2 (0.45) | CAPN1MEN1TSHRKMT2ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |