Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028183 | 0.90 | PSMB5 (0.37) | RENPSMB5MMP1HSP90AA1HSP90AB1 | |
| SCHEMBL28028172 | 0.87 | MEN1 (0.41) | RENPSMB5MMP1CTSD | |
| SCHEMBL28821803 | 0.85 | MEN1 (0.44) | CTSD | |
| SCHEMBL28028173 | 0.84 | CTSD (0.35) | RENPSMB5MMP1MMEHSP90AA1 | |
| SCHEMBL5707491 | 0.83 | PSMB1 (0.47) | RENPSMB5MMEPSMB1LTA4H | |
| SCHEMBL21457977 | 0.75 | CAPN1 (0.50) | MMP1MMELTA4H | |
| SCHEMBL15299885 | 0.71 | MEN1 (0.47) | RENPSMB5PSMB1CTSD | |
| SCHEMBL21458071 | 0.70 | MMP1 (0.44) | MMP1LTA4H | |
| SCHEMBL17596479 | 0.69 | LAP3 (0.50) | RENMMEPSMB1CTSDLTA4H | |
| Hydrochloric Acid SCHEMBL20474482 | 0.68 | LAP3 (0.49) | RENMMEPSMB1CTSDLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |