Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821803 | 0.97 | MEN1 (0.44) | MEN1TSHRKMT2ACAPN1BACE1 | |
| SCHEMBL28027550 | 0.87 | REN (0.40) | PSMB5CTSDMMP1REN | |
| SCHEMBL28028173 | 0.85 | CTSD (0.35) | PSMB5CTSDMMP1REN | |
| SCHEMBL28028183 | 0.84 | PSMB5 (0.37) | PSMB5CTSKCTSDMMP1REN | |
| SCHEMBL15299885 | 0.84 | MEN1 (0.47) | MEN1TSHRKMT2ACAPN1BACE1 | |
| SCHEMBL21458026 | 0.78 | MEN1 (0.46) | MEN1TSHRKMT2ACAPN1REN | |
| SCHEMBL21457988 | 0.76 | CAPN1 (0.64) | MEN1TSHRKMT2ACAPN1PSMB5 | |
| SCHEMBL28028156 | 0.76 | CAPN1 (0.37) | MEN1TSHRKMT2ACAPN1BACE1 | |
| SCHEMBL5707491 | 0.72 | PSMB1 (0.47) | PSMB5REN | |
| SCHEMBL21555137 | 0.70 | SMN1; SMN2 (0.45) | MEN1TSHRKMT2ACAPN1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |