Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 14/20 | 0.66 |
| ▸ | METAP1 | P53582 | 6/20 | 0.66 |
| ▸ | LAP3 | P28838 | 2/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.56 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028169 | 1.00 | METAP2 (0.66) | METAP2METAP1LAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL21458088 | 0.99 | METAP2 (0.64) | METAP2METAP1LAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL3841230 | 0.99 | METAP2 (0.64) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL8494993 | 0.85 | LAP3 (0.70) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL20474481 | 0.85 | LAP3 (0.70) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL5227811 | 0.85 | LAP3 (0.70) | METAP2METAP1LAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL3841335 | 0.84 | LAP3 (0.68) | METAP2METAP1LAP3ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL20474460 | 0.84 | LAP3 (0.68) | METAP2METAP1LAP3ANPEPRNPEP | |
| SCHEMBL8309569 | 0.81 | TSHR (0.53) | METAP2METAP1TSHRCTSC | |
| SCHEMBL20834910 | 0.81 | TSHR (0.53) | METAP2METAP1TSHRCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |