Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 12/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960950 | 0.77 | TSHR (0.50) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL31319423 | 0.77 | KCNK2 (0.49) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL23141266 | 0.76 | KCNK2 (0.55) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL24616726 | 0.76 | LMNA (0.59) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL9367905 | 0.73 | MCL1 (0.61) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL6926906 | 0.73 | MRGPRX4 (0.43) | ADRA2BADRA2CTAS2R14ALDH1A1KDM4E | |
| SCHEMBL11764782 | 0.73 | KCNK2 (0.46) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL23141167 | 0.72 | LMNA (0.51) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL22519100 | 0.72 | MAPT (0.72) | KCNK2KCNK10LMNAMAPTTSHR | |
| SCHEMBL5667262 | 0.72 | ACMSD (0.46) | TSHRALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804348-B | A kind of close electric trifluoromethylthio reagent, synthetic method and application thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-10-14 | — | — | CN | disclosed |