Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167087 | 0.81 | MAPT (0.47) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28848644 | 0.80 | MAPT (0.46) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28821890 | 0.80 | PSMD14 (0.50) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28028256 | 0.80 | MAPT (0.62) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28167250 | 0.80 | ALDH1A1 (0.46) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28848667 | 0.77 | MAPT (0.43) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28028730 | 0.77 | HDAC1 (0.36) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL32679860 | 0.76 | PDE10A (0.67) | PDE10ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL28821889 | 0.76 | POLB (0.60) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3969185 | 0.76 | KDM4E (0.54) | PDE10ANPC1MEN1KMT2ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860880-B | The method of one kind 8 (nitromethyla) quinolines of synthesis | 浙江工业大学 | 2017-07-28 | — | — | CN | claimed |
| CN-104860880-A | Method for synthesizing 8-(nitro methyl) quinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | claimed |
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | claimed |
| CN-104860880-B | The method of one kind 8 (nitromethyla) quinolines of synthesis | 浙江工业大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |
| CN-104860880-A | Method for synthesizing 8-(nitro methyl) quinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |
| CN-104860880-A | Method for synthesizing 8-(nitro methyl) quinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |
| CN-104860880-A | Method for synthesizing 8-(nitro methyl) quinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |