Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167087 | 0.84 | MAPT (0.47) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL28821890 | 0.82 | PSMD14 (0.50) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL28028256 | 0.82 | MAPT (0.62) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL28167250 | 0.82 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL28848667 | 0.80 | MAPT (0.43) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL28028248 | 0.80 | PDE10A (0.57) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL11942314 | 0.80 | MCHR1 (0.44) | MAPTALDH1A1L3MBTL1CASP6KDM4E | |
| SCHEMBL3934978 | 0.78 | MEN1 (0.45) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL6634465 | 0.77 | HSP90AA1 (0.68) | MAPTALDH1A1L3MBTL1NPC1CASP6 | |
| SCHEMBL1229233 | 0.76 | MEN1 (0.47) | MAPTALDH1A1L3MBTL1NPC1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860880-B | The method of one kind 8 (nitromethyla) quinolines of synthesis | 浙江工业大学 | 2017-07-28 | — | — | CN | disclosed |