Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027642 | 0.82 | MEN1 (0.38) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL358629 | 0.82 | MAPT (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL2143638 | 0.82 | MEN1 (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1025814 | 0.82 | MAPT (0.48) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL404980 | 0.82 | TSHR (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL2246946 | 0.82 | TDP1 (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL2246907 | 0.78 | LMNA (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL2246090 | 0.78 | TP53 (0.41) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL18606313 | 0.78 | VCAM1 (0.47) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL2248311 | 0.78 | CRHBP (0.53) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574845-B | 1H-imidazo [4,5-c] qualone derivative | NOVARTIS AG (CH) | 2015-09-02 | — | — | CN | disclosed |