Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219902 | 0.91 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL12667879 | 0.82 | CHRNB2 (0.62) | CHRNB2CHRNA4 | |
| SCHEMBL6750074 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL29656789 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL30461625 | 0.79 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL19875367 | 0.79 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL31742565 | 0.77 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL11062191 | 0.77 | KCNA3 (0.58) | — | |
| SCHEMBL23745944 | 0.76 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL1875084 | 0.76 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812755-A | Pyrazolopyridine derivatives as TTX-S blockers | RAQUALIA PHARMA INC | 2015-07-29 | — | — | CN | disclosed |