Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848420 | 0.86 | ADRA2C (0.43) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL2848296 | 0.85 | GABRA1 (0.49) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL12227223 | 0.84 | KDM4E (0.64) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL9625908 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL4280451 | 0.84 | HTT (0.51) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL2846372 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL29173230 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL2849222 | 0.83 | ADRA2C (0.41) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL2849190 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1ADRA2CHTR1AADRB2 | |
| SCHEMBL9627195 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1ADRA2CHTR1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812790-A | Organopolysiloxane graft polymer | KAO CORP | 2015-07-29 | — | — | CN | disclosed |