Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 17/20 | 0.56 |
| ▸ | BCR | P11274 | 14/20 | 0.56 |
| ▸ | PRKCA | P17252 | 8/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.54 |
| ▸ | SRC | P12931 | 9/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | PRKACG | P22612 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28371930 | 0.84 | NR4A1 (0.67) | NR4A1ABL1BCRPRKCAPRKCD | |
| SCHEMBL28376014 | 0.80 | ABL1 (0.67) | NR4A1ABL1BCRPRKCAPRKCD | |
| SCHEMBL28541022 | 0.79 | NR4A1 (0.73) | NR4A1ABL1BCRPRKCAPRKCD | |
| SCHEMBL28376597 | 0.79 | NR4A1 (0.71) | NR4A1ABL1BCRPRKCAPRKCD | |
| SCHEMBL28229485 | 0.78 | MMP13 (0.67) | NR4A1ABL1BCRPRKCASRC | |
| SCHEMBL28546947 | 0.77 | NR4A1 (0.66) | NR4A1ABL1BCRPRKCAPRKCD | |
| SCHEMBL28377492 | 0.77 | NR4A1 (0.66) | NR4A1ABL1BCRPRKCAPRKCD | |
| SCHEMBL28373418 | 0.76 | NR4A1 (0.68) | NR4A1ABL1BCRPRKCAPRKCD | |
| SCHEMBL28542549 | 0.76 | SYK (0.69) | NR4A1 | |
| SCHEMBL28376736 | 0.76 | ABL1 (0.61) | NR4A1ABL1BCRPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829597-A | 1H-indol-2-carbohydrazide derivative as well as preparation method and use of derivative | UNIV XIAMEN | 2015-08-12 | — | — | CN | disclosed |