Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 4/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28067809 | 0.80 | PSMB5 (0.47) | PSMB5GRIN2BCAMKK2GSK3BKDM4E | |
| SCHEMBL28821843 | 0.77 | KDM4E (0.52) | MEN1KMT2AKDM4EAXLCDK8 | |
| SCHEMBL28028252 | 0.75 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28028733 | 0.69 | CKS1B (0.47) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28167218 | 0.67 | KDM4E (0.40) | GRIN2BKMT2AKDM4EAXLALDH1A1 | |
| SCHEMBL28028249 | 0.64 | MAPT (0.61) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28167297 | 0.64 | PDGFRB (0.43) | PSMB5MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13886860 | 0.64 | PSMB5 (0.68) | PSMB5SMN1; SMN2GSK3BGSK3AAXL | |
| SCHEMBL701265 | 0.63 | HSD17B10 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6538299 | 0.62 | KDM4E (0.58) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |
| CN-104860880-A | Method for synthesizing 8-(nitro methyl) quinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |