Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028249 | 0.82 | MAPT (0.61) | MEN1KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL10157939 | 0.80 | HTT (0.58) | MEN1KMT2ASMN1; SMN2HTTPSMD14 | |
| SCHEMBL28028733 | 0.78 | CKS1B (0.47) | MEN1KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL11973580 | 0.76 | MEN1 (0.77) | MEN1KMT2ASMN1; SMN2HTTPSMD14 | |
| SCHEMBL28067774 | 0.76 | HTT (0.56) | MEN1KMT2ASMN1; SMN2HTTPSMD14 | |
| SCHEMBL28028770 | 0.75 | PSMB5 (0.42) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28028248 | 0.74 | PDE10A (0.57) | MEN1KMT2ASMN1; SMN2HTTPSMD14 | |
| SCHEMBL28028923 | 0.73 | LMNA (0.50) | MEN1KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL812451 | 0.72 | HTT (0.70) | MEN1KMT2ASMN1; SMN2HTTPSMD14 | |
| SCHEMBL8342933 | 0.72 | PAX8 (0.59) | KMT2ASMN1; SMN2HTTPSMD14COPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860880-B | The method of one kind 8 (nitromethyla) quinolines of synthesis | 浙江工业大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-104860880-A | Method for synthesizing 8-(nitro methyl) quinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |