Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | CTH | P32929 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093675 | 0.86 | KMT2A (0.68) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29066522 | 0.85 | MAPT (0.61) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28028252 | 0.82 | MEN1 (0.54) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28900353 | 0.80 | MAPT (0.59) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12643763 | 0.79 | MAPT (0.61) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28028733 | 0.78 | CKS1B (0.47) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL21816802 | 0.78 | MAPT (0.69) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2555260 | 0.76 | MAPT (0.67) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6609076 | 0.76 | ALDH1A1 (0.77) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8345364 | 0.76 | MAPT (0.67) | MAPTALDH1A1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |