Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 7/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 7/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028249 | 0.78 | MAPT (0.61) | ALDH1A1L3MBTL1MAPTCYP2D6CYP2C9 | |
| SCHEMBL28028252 | 0.78 | MEN1 (0.54) | ALDH1A1L3MBTL1MAPTCYP2D6CYP2C9 | |
| SCHEMBL10300323 | 0.75 | CKS1B (0.58) | CKS1BSKP2GLO1L3MBTL1MAPT | |
| SCHEMBL8116134 | 0.72 | MAPT (0.61) | ALDH1A1L3MBTL1MAPTKDM4EMAPK1 | |
| SCHEMBL28028248 | 0.71 | PDE10A (0.57) | ALDH1A1L3MBTL1MAPTCOMTCYP2D6 | |
| SCHEMBL1170421 | 0.70 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2A | |
| SCHEMBL6558016 | 0.70 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPTCYP2D6CYP2C19 | |
| SCHEMBL28028770 | 0.69 | PSMB5 (0.42) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12530867 | 0.69 | COMT (0.73) | CKS1BSKP2GLO1ALDH1A1L3MBTL1 | |
| SCHEMBL8035529 | 0.69 | PSMD14 (0.56) | CKS1BSKP2GLO1COMTTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860881-A | Methods for synthesizing 8-(nitro methyl) quinoline compounds and 8-methylamino tetrahydroquinoline compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-08-26 | — | — | CN | disclosed |