SCHEMBL28028829

SCHEMBL28028829

CCS(=O)(=O)NCc1cccc2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.68
NQO2 P16083 1/20 0.55
MC5R P33032 2/20 0.46
MC1R Q01726 1/20 0.46
GUSB P08236 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA4 P22748 1/20 0.46
CA9 Q16790 1/20 0.46
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
ATM Q13315 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10312248 0.84 NQO2 (0.71) CA2NQO2MC5RGUSBCA12
SCHEMBL31594624 0.84 NQO2 (0.71) CA2NQO2MC5RGUSBCA12
SCHEMBL28028830 0.83 CA2 (0.64) CA2NQO2MC5RCA12CA1
SCHEMBL21034642 0.81 CA2 (0.70) CA2NQO2MC5RMC1RGUSB
SCHEMBL4270510 0.81 CA2 (1.00) CA2NQO2MC5RMC1RCA12
SCHEMBL4770153 0.78 CA2 (0.66) CA2NQO2GUSBCA12CA1
SCHEMBL20906520 0.77 CA2 (0.64) CA2NQO2MC5RMC1RGUSB
SCHEMBL19636715 0.76 MEN1 (0.68) CA2NQO2CA12CA9MEN1
SCHEMBL30365968 0.75 CYP1A2 (0.59) CA2NQO2MEN1MAPTKMT2A
SCHEMBL47 0.75 CYP1A2 (0.59) CA2NQO2MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104969406-A Electrolyte solution for electrochemical device and electrochemical device WAKO PURE CHEM IND LTD 2015-10-07 CN disclosed