SCHEMBL19636715

SCHEMBL19636715

Cc1ccc(S(=O)(=O)NCc2cccc3ccccc23)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
CYP1A2 P05177 2/20 0.59
CYP3A4 P08684 2/20 0.59
CA2 P00918 1/20 0.59
CA12 O43570 1/20 0.59
ATM Q13315 1/20 0.59
CA9 Q16790 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CYP19A1 P11511 1/20 0.57
GAA P10253 2/20 0.51
HKDC1 Q2TB90 1/20 0.51
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
HTT P42858 2/20 0.51
MAPT P10636 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
THRB P10828 1/20 0.49
NQO2 P16083 1/20 0.49
KEAP1 Q14145 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4770153 0.88 CA2 (0.66) MEN1KMT2ACA2CA12CA9
SCHEMBL28113723 0.85 CA2 (0.63) MEN1KMT2ACYP3A4CA2CA12
SCHEMBL4874695 0.83 CYP19A1 (0.61) MEN1KMT2ACA2CA12CA9
SCHEMBL12406975 0.81 KMT2A (1.00) MEN1KMT2ACYP1A2CYP3A4CA12
SCHEMBL4492832 0.80 MEN1 (0.51) MEN1KMT2ACYP1A2CYP3A4CA2
SCHEMBL5960083 0.79 KMT2A (0.72) MEN1KMT2ACYP1A2CYP3A4CA12
SCHEMBL29048576 0.79 MEN1 (0.72) MEN1KMT2ACYP1A2CYP3A4CA2
SCHEMBL29128000 0.79 KMT2A (0.72) MEN1KMT2ACYP1A2CYP3A4CA12
SCHEMBL7521985 0.79 KMT2A (0.72) MEN1KMT2ACYP1A2CYP3A4CA12
SCHEMBL4872425 0.79 CA2 (0.53) MEN1KMT2ACA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112047865-B Method for synthesizing N-alkyl sulfonamide in water 南京理工大学 2022-12-02 CN disclosed
CN-112047865-A Method for synthesizing N-alkyl sulfonamide in water 南京理工大学 2020-12-08 CN disclosed
WO-2017197670-A1 METHOD FOR SYNTHESIZING 1,2-DIMETHYLENE CYCLOBUTANE CHIRAL COMPOUND 中国科学院福建物质结构研究所 2017-11-23 WO disclosed