Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636715 | 0.88 | MEN1 (0.68) | CA2KEAP1MEN1KMT2ANQO2 | |
| SCHEMBL8858490 | 0.84 | NQO2 (0.68) | CA2RECQLNQO2LMNASMN1; SMN2 | |
| SCHEMBL29540801 | 0.84 | KEAP1 (0.70) | CA2KEAP1MEN1KMT2ALMNA | |
| SCHEMBL4874695 | 0.83 | CYP19A1 (0.61) | CA2MEN1KMT2ANQO2LMNA | |
| SCHEMBL4872425 | 0.81 | CA2 (0.53) | CA2MEN1KMT2ACA12CA1 | |
| SCHEMBL1402910 | 0.80 | HDAC2 (0.57) | CA2RECQLMEN1KMT2ALMNA | |
| SCHEMBL1402907 | 0.80 | HDAC2 (0.57) | CA2RECQLMEN1KMT2ALMNA | |
| SCHEMBL31594624 | 0.79 | NQO2 (0.71) | CA2KEAP1MEN1KMT2ANQO2 | |
| SCHEMBL4270510 | 0.79 | CA2 (1.00) | CA2MEN1KMT2ANQO2CA12 | |
| SCHEMBL21034642 | 0.79 | CA2 (0.70) | CA2MEN1KMT2ANQO2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588697-B | Disubstituted benzenes sulfamide compound of one class 2,5 and its production and use | 中国科学院上海药物研究所 | 2017-09-15 | — | — | CN | claimed |
| CN-103588697-B | Disubstituted benzenes sulfamide compound of one class 2,5 and its production and use | 中国科学院上海药物研究所 | 2017-09-15 | — | — | CN | disclosed |
| CN-104969406-A | Electrolyte solution for electrochemical device and electrochemical device | WAKO PURE CHEM IND LTD | 2015-10-07 | — | — | CN | disclosed |
| EP-2007760-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIZIN-3-ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007108569-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIZIN-3-ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-09-27 | — | — | WO | disclosed |