Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14398058 | 0.85 | KDM4E (0.46) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 | |
| SCHEMBL9853209 | 0.77 | MEN1 (0.43) | ALDH1A1ALOX15GAAKDM4ESMN1; SMN2 | |
| SCHEMBL28947795 | 0.76 | PTPRC (0.48) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 | |
| SCHEMBL12005783 | 0.75 | MYC (0.51) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 | |
| SCHEMBL36145 | 0.74 | ALDH1A1 (0.72) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 | |
| SCHEMBL30028907 | 0.74 | ALDH1A1 (0.72) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 | |
| SCHEMBL27497610 | 0.74 | CYP2C9 (0.49) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 | |
| SCHEMBL27470372 | 0.73 | NPC1 (0.49) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 | |
| SCHEMBL1774771 | 0.73 | BCAT2 (0.43) | ALDH1A1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL14398356 | 0.72 | NPSR1 (0.56) | CYP3A4CYP2C9ALOX12L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817532-B | A kind of preparation method of the ketone of 10 methoxyl group 4H benzos [4,5] cycloheptatriene [1,2 b] thiazole 4 | 浙江工业大学 | 2017-07-25 | — | — | CN | disclosed |
| CN-104817532-A | 10-methoxy-4H-benzo[4,5]cycloheptatriene[1,2-b]thiazol-4-one preparation method | UNIV ZHEJIANG TECHNOLOGY | 2015-08-05 | — | — | CN | disclosed |