Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549783 | 0.81 | MEN1 (0.44) | MEN1KMT2AMAPTPTPN2PTPN6 | |
| SCHEMBL9853151 | 0.79 | HDAC1 (0.42) | MEN1KMT2AMAPTPTPN2PTPN6 | |
| SCHEMBL28028973 | 0.77 | CYP3A4 (0.42) | KMT2APOLBALDH1A1MAPK1KDM4E | |
| SCHEMBL27597007 | 0.73 | PTPN1 (0.53) | MEN1KMT2AMAPTPTPN2PTPN6 | |
| SCHEMBL4784842 | 0.71 | — | — | |
| SCHEMBL8292435 | 0.71 | GAA (0.44) | MEN1KMT2AMAPTPTPN2PTPN6 | |
| SCHEMBL3801503 | 0.71 | KMT2A (0.40) | MEN1KMT2AMAPTPTPN2PTPN6 | |
| SCHEMBL15276735 | 0.70 | MEN1 (0.50) | MEN1KMT2AMAPTPTPN2PTPN6 | |
| SCHEMBL5552846 | 0.69 | ALDH1A1 (0.42) | MEN1KMT2AMAPTPTPN2PTPN6 | |
| SCHEMBL8257074 | 0.69 | MEN1 (0.38) | MEN1KMT2AMAPTPTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413293-A2 | 1-(Benzo[b]thienyl)-2-(thienyl) ethenes and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4904674-A | FREE OF AGGLOMERATION OF FIBRILLATION | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-02-27 | — | — | US | disclosed |