Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MYLK | Q15746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752076 | 0.89 | TMPRSS4 (0.54) | P2RX1TMPRSS4P2RX4P2RX7CA1 | |
| SCHEMBL28029365 | 0.88 | CA1 (0.49) | LMNAHTTSMN1; SMN2P2RX1TMPRSS4 | |
| SCHEMBL28029364 | 0.83 | ALDH1A1 (0.45) | LMNAHTTSMN1; SMN2P2RX1TMPRSS4 | |
| SCHEMBL28821920 | 0.83 | CA1 (0.44) | LMNAHTTSMN1; SMN2P2RX1TMPRSS4 | |
| SCHEMBL28105012 | 0.82 | TMPRSS4 (0.55) | P2RX1TMPRSS4P2RX4P2RX7CA1 | |
| SCHEMBL28029023 | 0.80 | KLKB1 (0.44) | LMNAHTTSMN1; SMN2P2RX1TMPRSS4 | |
| SCHEMBL27582539 | 0.78 | P2RX1 (0.54) | LMNAP2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL28029031 | 0.78 | AR (0.50) | LMNAP2RX1CA1CA2KMT2A | |
| SCHEMBL27599969 | 0.78 | TMPRSS4 (0.46) | P2RX1TMPRSS4P2RX4P2RX7CA1 | |
| SCHEMBL28821963 | 0.77 | CA1 (0.43) | LMNAP2RX1TMPRSS4P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | claimed |
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | disclosed |