Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029365 | 0.92 | CA1 (0.49) | CA1CA2KCNMA1P2RX1MGLL | |
| SCHEMBL28029364 | 0.86 | ALDH1A1 (0.45) | CA1CA2KCNMA1P2RX1MGLL | |
| SCHEMBL28752076 | 0.84 | TMPRSS4 (0.54) | CA1CA2P2RX1MGLLTMPRSS4 | |
| SCHEMBL28029025 | 0.83 | LMNA (0.52) | CA1CA2P2RX1MGLLTMPRSS4 | |
| SCHEMBL28029023 | 0.83 | KLKB1 (0.44) | CA1CA2KCNMA1P2RX1MGLL | |
| SCHEMBL28821963 | 0.80 | CA1 (0.43) | CA1CA2KCNMA1P2RX1MGLL | |
| SCHEMBL28105012 | 0.80 | TMPRSS4 (0.55) | CA1CA2P2RX1TMPRSS4P2RX4 | |
| SCHEMBL28029031 | 0.79 | AR (0.50) | CA1CA2KCNMA1P2RX1ALDH1A1 | |
| SCHEMBL27619537 | 0.76 | PARP1 (0.46) | CA1CA2KCNMA1P2RX1MGLL | |
| SCHEMBL27582539 | 0.76 | P2RX1 (0.54) | CA1CA2P2RX1TMPRSS4P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | claimed |
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | disclosed |