Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029365 | 0.85 | CA1 (0.49) | CA1CA2MAOBMAPTPKM | |
| SCHEMBL28029364 | 0.80 | ALDH1A1 (0.45) | CA1CA2KDM4EALDH1A1KMT2A | |
| SCHEMBL28821920 | 0.80 | CA1 (0.44) | CA1CA2MAPTALDH1A1KMT2A | |
| SCHEMBL28105012 | 0.79 | TMPRSS4 (0.55) | CA1CA2KMT2AP2RX1P2RX4 | |
| SCHEMBL28752076 | 0.78 | TMPRSS4 (0.54) | CA1CA2KMT2AMGLLP2RX1 | |
| SCHEMBL28029023 | 0.77 | KLKB1 (0.44) | CA1CA2MAPTPKMKDM4E | |
| SCHEMBL28029025 | 0.77 | LMNA (0.52) | CA1CA2ALDH1A1KMT2ATDP1 | |
| SCHEMBL28029031 | 0.75 | AR (0.50) | CA1CA2ARMAPTKDM4E | |
| SCHEMBL27582539 | 0.75 | P2RX1 (0.54) | CA1CA2KMT2AP2RX1LMNA | |
| SCHEMBL27619537 | 0.75 | PARP1 (0.46) | CA1CA2MAPTPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | claimed |
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | disclosed |