Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 8/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 8/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28835173 | 0.77 | CA1 (0.55) | MEN1KMT2ATMPRSS4P2RX1P2RX4 | |
| SCHEMBL28472299 | 0.76 | CES2 (0.53) | MEN1KMT2ACES2PDE2AHPGD | |
| SCHEMBL130628 | 0.75 | ALDH1A1 (0.59) | MEN1KMT2ACES2TMPRSS4KDM4E | |
| SCHEMBL17664303 | 0.74 | CES2 (0.59) | MEN1KMT2ACES2P2RX1ALDH1A1 | |
| SCHEMBL30062195 | 0.74 | CES2 (0.52) | MEN1KMT2ACES2TMPRSS4P2RX1 | |
| SCHEMBL27803367 | 0.74 | CES2 (0.52) | MEN1KMT2ACES2TMPRSS4P2RX1 | |
| SCHEMBL10786191 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2ACES2TMPRSS4KDM4E | |
| SCHEMBL27395327 | 0.74 | CES2 (0.52) | MEN1KMT2ACES2TMPRSS4P2RX1 | |
| SCHEMBL320481 | 0.74 | CES2 (0.52) | MEN1KMT2ACES2TMPRSS4P2RX1 | |
| SCHEMBL10455841 | 0.74 | CES2 (0.52) | MEN1KMT2ACES2TMPRSS4P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | claimed |
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | disclosed |