Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012062 | 0.85 | BRD4 (0.64) | BRD4FFAR4 | |
| SCHEMBL28012175 | 0.85 | BRD4 (0.64) | BRD4FFAR4LTA4H | |
| SCHEMBL15552984 | 0.85 | BRD4 (0.67) | BRD4 | |
| SCHEMBL28012051 | 0.83 | BRD4 (0.65) | BRD4FFAR4 | |
| SCHEMBL15538629 | 0.83 | BRD4 (0.61) | BRD4FFAR4MDM2 | |
| SCHEMBL28029723 | 0.83 | BRD4 (0.64) | BRD4 | |
| SCHEMBL15538361 | 0.83 | BRD4 (0.58) | BRD4FFAR4 | |
| SCHEMBL28029426 | 0.83 | BRD4 (0.58) | BRD4FFAR4 | |
| SCHEMBL15552670 | 0.83 | BRD4 (0.67) | BRD4 | |
| SCHEMBL15559351 | 0.83 | BRD4 (0.60) | BRD4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884451-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-09-02 | — | — | CN | disclosed |