Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012062 | 0.86 | BRD4 (0.64) | BRD4PTGS2FFAR4 | |
| SCHEMBL28012175 | 0.86 | BRD4 (0.64) | BRD4PTGS2FFAR4 | |
| SCHEMBL28012051 | 0.84 | BRD4 (0.65) | BRD4KDM4EPTGS2FFAR4 | |
| SCHEMBL15538629 | 0.84 | BRD4 (0.61) | BRD4PTGS2FFAR4 | |
| SCHEMBL15559351 | 0.83 | BRD4 (0.60) | BRD4PTGS2FFAR4 | |
| SCHEMBL28029416 | 0.83 | BRD4 (0.63) | BRD4FFAR4 | |
| SCHEMBL15539499 | 0.82 | BRD4 (0.62) | BRD4PTGS2FFAR4 | |
| SCHEMBL15538363 | 0.82 | BRD4 (0.59) | BRD4PTGS2FFAR4 | |
| SCHEMBL15541113 | 0.82 | BRD4 (0.58) | BRD4PTGS2FFAR4 | |
| SCHEMBL20135835 | 0.82 | BRD4 (0.58) | BRD4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884451-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-09-02 | — | — | CN | disclosed |