Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12838811 | 0.84 | ALDH1A1 (0.76) | ALDH1A1GAAL3MBTL1LMNAMEN1 | |
| SCHEMBL18767126 | 0.84 | POLB (0.71) | ALDH1A1HPGDSMN1; SMN2GAAPKM | |
| SCHEMBL18767128 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HPGDPTGER4SMN1; SMN2GAA | |
| SCHEMBL11851295 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HPGDPTGER4SMN1; SMN2PTGER2 | |
| SCHEMBL11848777 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HPGDPTGER4SMN1; SMN2GAA | |
| SCHEMBL18767127 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HPGDSMN1; SMN2GAAPKM | |
| SCHEMBL11854488 | 0.83 | NLRP3 (0.62) | ALDH1A1HPGDPTGER4SMN1; SMN2PTGER2 | |
| SCHEMBL18767129 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HPGDSMN1; SMN2GAAPKM | |
| SCHEMBL3687773 | 0.83 | PTGER4 (0.56) | ALDH1A1HPGDPTGER4SMN1; SMN2PTGER2 | |
| SCHEMBL4443073 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDL3MBTL1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237445-A | Synthetic process of 4-[2-(5-chloro-2-methoxy benzamide)ethyl]benzsulfamide | DALIAN JOIN KING BIOCHEM TECH CO LTD | 2016-01-13 | — | — | CN | claimed |
| CN-105237445-A | Synthetic process of 4-[2-(5-chloro-2-methoxy benzamide)ethyl]benzsulfamide | DALIAN JOIN KING BIOCHEM TECH CO LTD | 2016-01-13 | — | — | CN | disclosed |