Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14024225 | 0.86 | TACR3 (0.49) | ALDH1A1LMNANPSR1MEN1KMT2A | |
| SCHEMBL4448302 | 0.85 | PSMB5 (0.65) | ALDH1A1PSMB5MEN1KMT2ATACR3 | |
| SCHEMBL28029960 | 0.83 | ALDH1A1 (0.71) | ALDH1A1LMNAL3MBTL1NPSR1PSMB5 | |
| SCHEMBL12838811 | 0.78 | ALDH1A1 (0.76) | ALDH1A1LMNAL3MBTL1NPSR1KCNMA1 | |
| SCHEMBL31743126 | 0.77 | LMNA (0.69) | ALDH1A1LMNAL3MBTL1NPSR1KCNMA1 | |
| SCHEMBL3871499 | 0.77 | LMNA (0.69) | ALDH1A1LMNAL3MBTL1NPSR1KCNMA1 | |
| SCHEMBL17740367 | 0.77 | ALDH1A1 (0.77) | ALDH1A1LMNANPSR1KCNMA1MEN1 | |
| SCHEMBL14024226 | 0.77 | MEN1 (0.54) | ALDH1A1PSMB5MEN1KMT2ATACR3 | |
| SCHEMBL23355168 | 0.76 | ALDH1A1 (0.62) | ALDH1A1LMNAL3MBTL1NPSR1PSMB5 | |
| SCHEMBL4454245 | 0.74 | TACR3 (0.54) | KMT2ATACR3S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | CACNA1G, CACNA1H, CACNA1I | ALDH1A1 2335/4885LMNA 1070/4885L3MBTL1 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.