Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | POLA1 | P09884 | 2/20 | 0.48 |
| ▸ | POLG | P54098 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.44 |
| ▸ | PNP | P00491 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717128 | 0.82 | POLB (0.68) | TSHRPOLBPOLA1POLGHPRT1 | |
| SCHEMBL8720417 | 0.81 | MEN1 (0.58) | MEN1TSHRKMT2APOLBPOLA1 | |
| SCHEMBL9021892 | 0.78 | TSHR (0.81) | MEN1TSHRKMT2APOLGTAS1R3 | |
| SCHEMBL8444939 | 0.78 | MEN1 (0.80) | MEN1TSHRKMT2APOLGTAS1R3 | |
| SCHEMBL28030184 | 0.77 | POLB (0.56) | MEN1TSHRKMT2APOLBPOLA1 | |
| SCHEMBL7819447 | 0.76 | MEN1 (1.00) | MEN1TSHRKMT2APOLGTAS1R3 | |
| SCHEMBL7813656 | 0.76 | MEN1 (0.74) | MEN1TSHRKMT2ATAS1R3TAS1R1 | |
| SCHEMBL8447491 | 0.76 | MEN1 (0.83) | MEN1TSHRKMT2APOLGTAS1R3 | |
| SCHEMBL24316171 | 0.75 | POLB (0.67) | TSHRPOLBPOLA1POLGHPRT1 | |
| Bromide SCHEMBL7816191 | 0.75 | MEN1 (0.73) | MEN1TSHRKMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854228-A | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-12-29 | — | — | US | disclosed |
| US-5650510-A | VIRICIDES OR ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-07-22 | — | — | US | disclosed |
| EP-0269947-B2 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1996-10-16 | — | — | EP | disclosed |
| EP-0269947-A1 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1988-06-08 | — | — | EP | disclosed |