Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053483 | 0.83 | MEN1 (0.51) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL25938380 | 0.79 | MEN1 (0.37) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4320007 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL13886370 | 0.76 | MEN1 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL11502422 | 0.76 | GAA (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28184684 | 0.75 | NLRP3 (0.46) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL12581660 | 0.74 | KMT2A (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6908084 | 0.73 | MEN1 (0.44) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL6905835 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL1698306 | 0.73 | L3MBTL1 (0.44) | ALDH1A1MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103168027-B | Process for preparing cyclopropyl amide derivatives and intermediates related thereto | ASTRAZENECA AB (SE) | 2015-08-26 | — | — | CN | disclosed |