Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164122 | 0.76 | — | — | |
| SCHEMBL28847976 | 0.76 | — | — | |
| SCHEMBL27949116 | 0.74 | ALDH1A1 (0.31) | SLC6A3SLC6A4 | |
| SCHEMBL2050488 | 0.71 | — | — | |
| SCHEMBL28236096 | 0.65 | SLC6A4 (0.33) | SLC6A3SLC6A4 | |
| SCHEMBL548018 | 0.61 | ALDH1A1 (0.36) | — | |
| SCHEMBL8098112 | 0.60 | PNMT (0.32) | — | |
| SCHEMBL318771 | 0.60 | HRH3 (0.37) | — | |
| SCHEMBL10529159 | 0.60 | ESR2 (0.59) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7858287 | 0.60 | OPRM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947285-B | Sulfonamide derivatives as BCL-2-selective apoptosis inducers for the treatment of cancer and immune diseases | ABBVIE (US) | 2015-08-26 | — | — | CN | disclosed |