SCHEMBL28030586

SCHEMBL28030586

C=CC(=O)ON(CCCC)C(C)=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
HPGD P15428 1/20 0.47
THRB P10828 3/20 0.37
ATM Q13315 1/20 0.37
FAAH O00519 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
ZDHHC20 Q5W0Z9 3/20 0.34
ZDHHC2 Q9UIJ5 2/20 0.34
THRA P10827 1/20 0.34
HCAR2 Q8TDS4 3/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4018075 0.88 TSHR (0.46) TSHRHPGDTHRBATMFAAH
SCHEMBL1345555 0.83 TSHR (0.49) TSHRHPGDTHRBATMALDH1A1
SCHEMBL27682797 0.80 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL21412821 0.78 TSHR (0.50) TSHRHPGDTHRBATMFAAH
SCHEMBL17140759 0.77 TSHR (0.46) TSHRHPGDTHRBATMFAAH
Hydrochloric Acid SCHEMBL28285195 0.76 TSHR (0.48) TSHRHPGDTHRBATMFAAH
SCHEMBL16295067 0.76 NAAA (0.39) ATMALDH1A1CA12CA1CA9
Trimethylammonium SCHEMBL27893212 0.75 TSHR (0.47) TSHRHPGDTHRBATMFAAH
SCHEMBL745846 0.74 TSHR (0.41) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL3514262 0.74 DNM1 (0.40) TSHRALDH1A1CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103581-B Thermoplastic molding compounds having an optimum flow-toughness ratio 英力士苯领集团股份公司 2019-09-03 CN claimed
CN-109689054-A Antimicrobial polymers for ophthalmic implants 克拉梅德有限公司 2019-04-26 CN claimed
CN-103172809-B The method manufacturing graft copolymer 固特异轮胎和橡胶公司 2016-08-24 CN claimed
CN-103539946-B Hydrophobic polymer graft modification acrylamide polymer and preparation method thereof 中国石油化工股份有限公司 2016-06-08 CN claimed
CN-105451821-A Skin care formulations AKZO NOBEL CHEMICALS INT BV 2016-03-30 CN claimed
CN-105163811-A Sunscreen formulations AKZO NOBEL CHEMICALS INT BV 2015-12-16 CN claimed
CN-110505914-A Polymeric beads and its application IXOM OPERATIONS PTY LTD 2019-11-26 CN disclosed
CN-104698774-B semiconductor device process filter and method 台湾积体电路制造股份有限公司 2019-10-25 CN disclosed
CN-106103581-B Thermoplastic molding compounds having an optimum flow-toughness ratio 英力士苯领集团股份公司 2019-09-03 CN disclosed
CN-106232648-B Thermoplastic molding's compound with best residual monomer content 英力士苯领集团股份公司 2019-06-07 CN disclosed
CN-109689054-A Antimicrobial polymers for ophthalmic implants 克拉梅德有限公司 2019-04-26 CN disclosed
CN-109679002-A Catalytic component for olefin polymerization and preparation method thereof and catalyst and its application 中国石油化工股份有限公司 2019-04-26 CN disclosed
CN-109642147-A Method of producing a composite material BP探索操作有限公司 2019-04-16 CN disclosed
CN-104202978-B Agroformulation comprising copolymer of vinyl lactam, N-alkyl acrylamide and alkyl (meth) acrylate 巴斯夫欧洲公司 2016-06-22 CN disclosed
CN-105640798-A Ionic/ionogenic comb copolymer compositions and personal care products containing same 气体产品与化学公司 2016-06-08 CN disclosed
CN-103539946-B Hydrophobic polymer graft modification acrylamide polymer and preparation method thereof 中国石油化工股份有限公司 2016-06-08 CN disclosed
CN-105453306-A Binder for nonaqueous electricity storage element and nonaqueous electricity storage element KYORITSU CHEMICAL CO LTD 2016-03-30 CN disclosed
CN-105451821-A Skin care formulations AKZO NOBEL CHEMICALS INT BV 2016-03-30 CN disclosed
CN-105246500-A Matrix metalloproteinases and uses thereof ZYLBERBERG CLAUDIA 2016-01-13 CN disclosed
CN-105163811-A Sunscreen formulations AKZO NOBEL CHEMICALS INT BV 2015-12-16 CN disclosed