Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030586 | 0.88 | TSHR (0.47) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL1345555 | 0.81 | TSHR (0.49) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL27682797 | 0.79 | TSHR (0.39) | TSHRHPGDTHRB | |
| SCHEMBL21412821 | 0.77 | TSHR (0.50) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL17140759 | 0.76 | TSHR (0.46) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| Hydrochloric Acid SCHEMBL28285195 | 0.75 | TSHR (0.48) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| Trimethylammonium SCHEMBL27893212 | 0.74 | TSHR (0.47) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL745846 | 0.73 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL3948412 | 0.72 | THRB (0.47) | TSHRHPGDTHRBZDHHC2ALDH1A1 | |
| SCHEMBL13899887 | 0.71 | TSHR (0.48) | TSHRHPGDTHRBZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009088494-A1 | IMAGE RECORDING MEDIA AND IMAGE LAYERS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2009-07-16 | — | — | WO | claimed |
| WO-2009088494-A1 | IMAGE RECORDING MEDIA AND IMAGE LAYERS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2009-07-16 | — | — | WO | disclosed |