Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528195 | 0.95 | — | — | |
| SCHEMBL8078660 | 0.92 | MEN1 (0.50) | FAAHALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL23471380 | 0.90 | MEN1 (0.48) | FAAHALDH1A1MEN1KMT2ARECQL | |
| Toluene SCHEMBL27866094 | 0.86 | ITGB3 (0.47) | ALDH1A1MEN1KMT2ARECQLMAPT | |
| SCHEMBL28450124 | 0.82 | FAAH (0.43) | FAAHALDH1A1MEN1KMT2ARECQL | |
| Benzyl Bromide SCHEMBL28030652 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ARECQLMAPT | |
| SCHEMBL1767620 | 0.78 | FAAH (0.43) | FAAHALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL2807522 | 0.75 | EGLN1 (0.46) | FAAHALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL233413 | 0.75 | FAAH (0.55) | FAAHALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL31023073 | 0.75 | FAAH (0.49) | FAAHALDH1A1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106537145-A | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-105037248-B | A kind of synthetic method of Aiweimopan | 山东罗欣药业集团股份有限公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-106537145-A | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-102417463-B | The preparation method of alvimopan | 北京华禧联合科技发展有限公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-105037248-A | Synthesis method of alvimopan | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-11 | — | — | CN | disclosed |