SCHEMBL28030734

SCHEMBL28030734

CS(=O)(=O)Oc1c[c]ccc1C#N

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
ALPL P05186 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28030776 0.80 EPAS1 (0.33)
SCHEMBL15067272 0.78 KDM4E (0.37) ALDH1A1ALPLKDM4EKMT2AGAA
SCHEMBL8414710 0.77 GAA (0.47) ALDH1A1HTTKDM4EPOLBGAA
SCHEMBL233007 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EPOLBGAA
SCHEMBL15067412 0.75 KDM4E (0.32) KDM4EKMT2A
SCHEMBL9740475 0.75 PTPN1 (0.35) KDM4EKMT2APOLB
SCHEMBL15067717 0.75 KDM4E (0.32) ALDH1A1KDM4EKMT2A
SCHEMBL27962934 0.73 ALDH1A1 (0.41) ALDH1A1HTTPOLBPKM
SCHEMBL15066779 0.73 KDM4E (0.36) ALDH1A1ALPLKDM4EKMT2AGAA
SCHEMBL5844581 0.72 EPAS1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008378-A Reaction catalyst for cross coupling and method for manufacturing aromatic compound HOKKO CHEM IND CO 2015-10-28 CN disclosed