Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | HTR1D | P28221 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034327 | 0.83 | DRD2 (0.33) | ESR2DRD2HTR1DDRD3 | |
| SCHEMBL4443907 | 0.80 | SLC22A12 (0.40) | SLC22A12DRD2DRD3 | |
| SCHEMBL28030734 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL27941886 | 0.80 | HTR1A (0.31) | HTR1D | |
| SCHEMBL5366474 | 0.80 | CXCR2 (0.33) | DRD2HTR1DDRD3 | |
| SCHEMBL1180592 | 0.76 | SLC22A12 (0.34) | SLC22A12 | |
| SCHEMBL3958603 | 0.75 | EPAS1 (0.41) | EPAS1SLC22A12PGR | |
| SCHEMBL8024737 | 0.75 | CA2 (0.31) | — | |
| SCHEMBL3627292 | 0.74 | EPAS1 (0.38) | EPAS1PDE4APDE4CPDE4DSLC22A12 | |
| SCHEMBL5728291 | 0.73 | EPAS1 (0.45) | EPAS1PDE4APDE4CPDE4DSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008378-A | Reaction catalyst for cross coupling and method for manufacturing aromatic compound | HOKKO CHEM IND CO | 2015-10-28 | — | — | CN | disclosed |