Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SERPINH1 | P50454 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032991 | 0.81 | BACE1 (0.42) | MAPTALDH1A1HSP90AA1MAOAMAOB | |
| SCHEMBL8260518 | 0.75 | MAOA (0.48) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7354321 | 0.73 | MAOA (0.43) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL31219939 | 0.72 | MAOA (0.46) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL23106578 | 0.71 | MAOA (0.44) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL7354327 | 0.69 | MAOA (0.43) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27183235 | 0.69 | TDP1 (0.47) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL24398823 | 0.68 | MAOA (0.42) | MEN1KMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL7075420 | 0.68 | MTNR1A (0.41) | MEN1KMT2AALDH1A1MAOAMAOB | |
| SCHEMBL4087041 | 0.66 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945292-B | Process for preparing 4-propylthio-o-phenylenediamine | 济南大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-104945292-A | Process for preparing 4-propylthio-o-phenylenediamine | UNIV JINAN | 2015-09-30 | — | — | CN | disclosed |