Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031124 | 0.89 | DHODH (0.39) | GPR3TRIM58DHODHDHFRLMNA | |
| SCHEMBL28822264 | 0.85 | GPR3 (0.50) | GPR3LMNAHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL28031133 | 0.84 | GPR3 (0.45) | GPR3LMNAHPGDAHR | |
| SCHEMBL28031748 | 0.83 | GPR3 (0.40) | GPR3DHODHSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL28031120 | 0.82 | KDM4E (0.46) | LMNAHPGDSMN1; SMN2ACACANR1I3 | |
| SCHEMBL28031743 | 0.80 | MAT2A (0.40) | GPR3DHODHLMNA | |
| SCHEMBL28031664 | 0.79 | KDM4E (0.40) | GPR3DHODHLMNAHPGDSMN1; SMN2 | |
| SCHEMBL28031690 | 0.74 | NQO2 (0.42) | GPR3DHODHLMNA | |
| SCHEMBL28031135 | 0.74 | GPR3 (0.42) | GPR3SMN1; SMN2CYP1A2CYP3A4AHR | |
| SCHEMBL28031128 | 0.73 | DHODH (0.38) | DHODHCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844651-A | Method for preparing six fluorine phosphonic acid ester base fe organism derivatives | UNIV LUOYANG NORMAL | 2015-08-19 | — | — | CN | disclosed |