Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031122 | 0.89 | GPR3 (0.40) | DHODHGPR3TRIM58TSPOBRD4 | |
| SCHEMBL28822266 | 0.86 | GPR3 (0.47) | GPR3TSPOPARP1LMNAKDM4E | |
| SCHEMBL28031135 | 0.85 | GPR3 (0.42) | GPR3SMN1; SMN2KDM4E | |
| SCHEMBL28031751 | 0.84 | GPR3 (0.38) | DHODHGPR3SMN1; SMN2KDM4E | |
| SCHEMBL28031125 | 0.83 | KDM4E (0.44) | LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL28031746 | 0.81 | MAT2A (0.39) | DHODHGPR3ACP3LMNA | |
| SCHEMBL28031665 | 0.80 | PDE10A (0.40) | DHODHGPR3PARP1LMNASMN1; SMN2 | |
| SCHEMBL28031691 | 0.76 | KDM4E (0.41) | DHODHLMNAKDM4E | |
| SCHEMBL28031130 | 0.75 | DHODH (0.39) | DHODH | |
| SCHEMBL28031159 | 0.74 | KDM4E (0.38) | DHODHACP3PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844651-A | Method for preparing six fluorine phosphonic acid ester base fe organism derivatives | UNIV LUOYANG NORMAL | 2015-08-19 | — | — | CN | disclosed |