Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033083 | 0.83 | KMT2A (0.44) | FFAR1P2RY1HAO1KMT2AALDH1A1 | |
| SCHEMBL28030562 | 0.79 | HAO1 (0.45) | FFAR1FFAR4P2RY1HAO1PPARG | |
| SCHEMBL28822439 | 0.75 | CXCL8 (0.56) | ALDH1A1HPGDKDM4ESMN1; SMN2MRGPRX1 | |
| SCHEMBL28031195 | 0.75 | P2RY1 (0.42) | P2RY1HAO1KMT2AUSP2MEN1 | |
| SCHEMBL7313745 | 0.75 | KMT2A (0.54) | P2RY1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17624250 | 0.72 | MRGPRX1 (0.50) | FFAR1P2RY1KMT2AUSP2ALDH1A1 | |
| SCHEMBL5518685 | 0.71 | RAB9A (0.60) | P2RY1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL6136907 | 0.71 | P2RY1 (0.46) | P2RY1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL30748257 | 0.70 | CXCL8 (0.61) | PPARGPPARAPLAUSMN1; SMN2 | |
| SCHEMBL11447649 | 0.70 | CXCL8 (0.61) | PPARGPPARAPLAUSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037281-A | Preparation method for 3-(3-fluorophenoxyl)pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-11-11 | — | — | CN | disclosed |