Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031196 | 0.83 | FFAR1 (0.44) | KMT2AFFAR1ALDH1A1SMN1; SMN2HAO1 | |
| SCHEMBL28822439 | 0.79 | CXCL8 (0.56) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28035897 | 0.76 | KMT2A (0.47) | KMT2ATRPA1CYP3A4MAPK14SMN1; SMN2 | |
| SCHEMBL28033082 | 0.72 | CYP1A2 (0.43) | KMT2ATRPA1CYP3A4MAPK14LTA4H | |
| SCHEMBL3500048 | 0.72 | SRD5A2 (0.62) | KMT2AS1PR2LTA4HFFAR1 | |
| SCHEMBL28018126 | 0.72 | GABRR1 (0.42) | ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL2779361 | 0.71 | KMT2A (0.65) | KMT2AALDH1A1 | |
| SCHEMBL7371142 | 0.70 | KMT2A (0.59) | KMT2AALDH1A1 | |
| SCHEMBL9486549 | 0.69 | CAMK2A (0.48) | FFAR1ALDH1A1CYP1A2 | |
| SCHEMBL27566728 | 0.68 | SCN9A (0.54) | KMT2ALTA4HFFAR1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961690-A | Preparation method of 3-(4-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| CN-104961691-A | Preparation method of 3-(2-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |