Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201268 | 0.91 | TSHR (0.39) | TSHROPRM1OPRL1AKR1B1LMNA | |
| SCHEMBL28102974 | 0.78 | LMNA (0.44) | TSHRLMNA | |
| SCHEMBL21753776 | 0.73 | LMNA (0.42) | TSHRLMNA | |
| SCHEMBL28200687 | 0.72 | NR5A2 (0.36) | TSHROPRM1OPRL1DPP4OPRD1 | |
| SCHEMBL15848612 | 0.70 | BCHE (0.37) | OPRM1OPRL1 | |
| SCHEMBL27740112 | 0.68 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL5139043 | 0.66 | TSHR (0.43) | TSHROPRM1OPRL1LMNAALDH1A1 | |
| SCHEMBL21638945 | 0.66 | TSHR (0.43) | TSHROPRM1OPRL1LMNAALDH1A1 | |
| SCHEMBL4368396 | 0.66 | TSHR (0.39) | TSHROPRM1OPRL1DPP4OPRD1 | |
| SCHEMBL25297073 | 0.66 | TACR1 (0.41) | TSHROPRM1OPRL1POLBOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105007732-A | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-10-28 | — | — | CN | disclosed |